He spent nearly five minutes in front of the image of Mexico's patron saint.
The Pope said that he went into a "Time Tunnel" with a set of movies he received this week.
They will talk for some 10 minutes in the presidential hangar of Mexico City.
Francis said that his deepest desire for his trip to Mexico is to pray before the shrine of the Virgin of Guadalupe.
El hallazgo, realizado en la universidad de Estrasburgo, era parte de la colección de esqueletos y órganos de judíos reunida por el anatomista nazi August Hirt